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Dr.Arun Balakrishnan


Education

Post Doctoral Research Associate 1985-1989 University of California, Berkeley, USA
Ph.D.(BioChemistry) University of Madras, Chennai 1985 Cancer Research Institute
M.S.(Biochemistry) Chennai 1980 University of Madras








Teaching Experience

1993 to present Offering and elective course in Cancer Biology for the M.Tech Program at Centre for Biotechnology, Anna University.

1989 to present Currently teaching Cell Biology, Biochemistry, Viruses, and Cancer to M.Tech and B.Tech students at the Centre for Biotechnology, Anna University.

Trained and assisted Graduate students in Ph.D. program at the Cancer Research Laboratory, Department of Zoology, University of California, Berkeley, USA.

Conducted classes in Biochemistry and Endocrinology for under graduate and graduate students at the Department of Biochemistry, University of Madras.


Training Programs


Training at University of Leicester, Department of Genetics, Leicester, U.K. in the area of signal transduction (From Oct.1991 - Jan'93)

Participated in the ongoing interaction on signal transduction with University of Leicester(From May 1994 - Aug'94)

Visited Department of Tropical Medicine, National Institute of Health, USA for research with filariasis group (Aug'94)

Participated in Technology Management workshop, Organized by United States International University, San Diego, USA and COSTED, India at USIU(June 98)

M.Tech Program(By Research)


Analysis of the synthesis and secretion of silk proteins in Bombyx mori Rajan, M.K.Rajan, M.K.(1991)

Cloning and expression of collagen gene in Escherichia coli Veena J. (1992)

cloning and expression of human granulocyte macrophage colony stimulating Factor(h-GMCSF) in pSE420. Kannan K.(1993)

Cloning and expression of human granulocyte macrophage colony stimulating Factor(h-GMCSF)-cDNA using T7 expression system in Escherichia coli. Murugan, V.(1994)

Development of a DNA probe for monitoring the transcriptional level expression of silk Fibroin fene Padmesh, P.(1995)

Study of pathogenesis of Klebsiella pneumonia infection on lung epithelial cells Gopinathan, C. (1995)

Ph.D.Program


An in vitro model to analyse lung epithelial proliferation and modulation of cellular responses by filarial proteins - Maya,A.1996

An in vitro study to understand mitogenic potential of linoleate or lung epithelial Cells - a cellular and molecular approach - Usha, S.(1996)

cDNA probe to detect the stage and site specific expression of fibroin insilkworm Bombyx mori - Rajan,M.K(1997)

An in vitro study to elucidate cellular responses during Klebsiella pneumoniae infection of lung cells - Nagalakshmi M.L.(1998)

Major areas of research expertise


Estrogen receptors in Breast cancers and developed models for studies in carcinogenesis in mammary cancers inrats -(1980-1984)

Understanding normal cell proliferation of human breast epithelial cells and the development of an invitro three-dimensional collagen gel cultures.; transplantation studies in Nude athymic mice. 1985-1989

Establishment of a cell culture facility to understand pathogenesis, specially to evaluate direct interaction of filarial parasitic proteins on lung epithelial cell, with a view to understand the cellular and molecular level changes that may occur prior to cell destruction.

Invitro models to study bacterial - host cell interactions, specifically for klebsiella Pneumonia and Enteropathogenic E coli. Study directed to identifying new toxins and implicating a role in pathogenesis.

Construction of specific expression systems for the production of IFN and GMCSF. Construction of cDNA library for identification of fibrion expression in Bombyx Mori

Bioprospecting and screening of Biological properties of medicinal plants using Invitro techniques towards new Drug Development.

Research Grants


Development of an invotro model to study filarial parasitic interaction with lung epithelial cells invitro, 1991 to 1998, funded by Schering Plough Inc, USA (Rs.10.25 lakhs).

Understanding Klebsiella infection in lung - An invitro model to delineate pathogenesis at a cellular and molecular level, 1996 to 1999 funded by Torrent Pharmaceuticals (Rs.2.5 lakhs)

Studies to unravel the intricacies involved in enteropathogenic E.Coli infection and pathogenesis, 1997 to 2000, funded by Department of Science and Technology New Delhi (Rs.12.3 lakhs)

Studies on Helicobacter pylori infection, a multicentric study 1997 to 2000, funded by Department of Biotechnology, New Delhi., Co PI(Rs. 6.0 lakhs)
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E-mail: arunb@annauniv.edu